David Ouyang

Staff Physician and Assistant Professor
Smidt Heart Institute and Division of Artificial Intelligence in Medicine
Cedars-Sinai Medical Center
127 S San Vicente Blvd, Los Angeles, CA
david.ouyang@cshs.org
[CV]

I am a cardiologist and researcher in the Department of Cardiology and Division of Artificial Intelligence in Medicine at Cedars-Sinai Medical Center. Our group works on applications of deep learning, computer vision, and the statistical analysis of large datasets within cardiovascular medicine. As an echocardiographer, I apply deep learning for precision phenotyping in cardiac ultrasound and the deployment and clinicial trials of AI models. Our work has been published in Nature, Nature Medicine, JAMA Cardiology, Circulation, NEJM AI, and other scientific venues.

As a physician-scientist and statistician with focus on cardiology and imaging, I majored in statistics at Rice University, obtained my MD at UCSF, and received post-graduate medical education in internal medicine, cardiology, and a postdoc in computer science and biomedical data science at Stanford University.

Our group works on multi-modal datasets, linking EHR, ECG, echo, and MRI data for a broad perspective on cardiovascular disease and have diverse backgrounds (ranging from physics, mechanical engineering, computer science to cardiology, anesthesia, and internal medicine). We are recruiting postdoctoral fellows and research scientists with background in computer vision and NLP (extensive prior experience with Pytorch, TorchVision, Huggingfaces libraries). If you're interested in improving cardiovascular imaging and cardiovascular care, please email me!

Precision Phenotyping of Echocardiography

• Ouyang D*, He B, Ghorbani A, Langlotz CP, Heidenreich PA, Harrington RA, Liang DH, Ashley EA, Zou JY* “Video-based artificial intelligence for beat-to-beat assessment of cardiac function ” Nature. March 25, 2020.
• Duffy G*, Cheng PP*, Yuan*,He B, Kwan AC, Shun-Shin MJ, Alexander KM, Ebinger J, Lungren MP, Rader F, Liang DH, Schnittger I, Ashley EA, Zou JY, Patel J, Witteles R, Cheng S^, Ouyang D^. “High-Throughput Precision Phenotyping of Left Ventricular Hypertrophy With Cardiovascular Deep Learning.” JAMA Cardiology February 23, 2022. *Co-First author ^Co-Corresponding author [Dataset is at https://echonet.github.io/lvh/]
• Reddy CD, Lopez L, Ouyang D, Zou JY, He B. “Video-Based Deep Learning for Automated Assessment of Left Ventricular Ejection Fraction in Pediatric Patients”. Journal of the American Society of Echocardiography February 7, 2023.
• Ouyang D, He B, Gorbhani A, Lungren MP, Ashley EA, Liang DH, Zou JY. “EchoNet-Dynamic: a Large New Cardiac Motion Video Data Resource for Medical Machine Learning”. NeurIPS Machine Learning for Health Workshop December 5, 2019. [Dataset is at https://echonet.github.io/dynamic/]

AI Clinical Trials and Deployment

• He B, Kwan AC, Cho JH, Yaun N, Pollick C, Shiota T, Ebinger J. Bello NA, Wei J, Josan K, Duffy G, Jujjavarapu M, Siegel R, Cheng S*, Zou JY*. Ouyang D*. “EchoNet-RCT: Blinded, Randomized Controlled Trial of Sonographer vs. Artificial Intelligence Assessment of Cardiac Function.” Nature 2023
• Wu E, Wu K, Daneshjou R, Ouyang D, Ho D, Zou JY. “How medical AI devices are evaluated: limitations and recommendations from an analysis of FDA approvals.” Nature Medicine April 5, 2021.
• Ongoing , “Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening).”
• Ongoing , “Safety and Efficacy Study of AI Wall Thickness Measurement (EchoNet-LVH-RCT).”

Deep Phenotyping

• Gorbhani A*, Ouyang D*^, Abid A, He B, Chen JH, Harrington RA, Liang DH, Ashley EA, Zou JY^. “Deep Learning Interpretation of Echocardiograms.” npj Digital Medicine. January 24, 2020.
• Duffy G, Clarke SL, Christensen M, He B, Yuan N, Cheng S, Ouyang D* “Confounders mediate AI prediction of demographics in medical imaging” npj Digital Medicine. ” December 22, 2022.
• Weston HJ, Yuan N, He B, Ouyang J, Ebinger J, Botting P, Lee J, Theurer J, Tooley JE, Neiman K, Lungren MP, Liang D, Schnittger I, Harrington B, Chen JH, Ashley EA, Cheng S, Ouyang D^, Zou JY^. “Deep learning evaluation of biomarkers from echocardiogram videos.” EbioMedicine October 13, 2021.
• Ouyang D*, Zou JY “Deep learning models to detect hidden clinical correlates.” The Lancet Digital Health. ” July 2, 2020.
• Yuan N, Kwan AC, Duffy G, Theurer J, Chen JH, Nieman K, Botting P, Dey D, Berman DS, Cheng S, Ouyang D*. “Prediction of Coronary Artery Calcium Using Deep Learning of Echocardiograms.” Journal of the American Society of Echocardiography ” December 23, 2022.

Healthcare Data Science

• Ouyang D*, Gulati G, Ha R, Banerjee D. “Incidence of Temporary Mechanical Circulatory Support Prior to Heart Transplantation and Impact on Post-Transplant Outcomes.” Journal of Heart and Lung Transplantation Apr 26, 2018.
• Ouyang D*, Tisdale R, Cheng P, Chi J, Ashley EA, Chen JH. “Acetaminophen or Tylenol? A Retrospective Analysis of Medication Digital Communication Practices.” Journal of General Internal Medicine May 1, 2018.
• Ouyang D*, Chen J, Krishnan G, Hom J, Witteles R, Chi J. “Patient Outcomes When Housestaff Exceed Eighty Hours per Week.” American Journal of Medicine. April 18, 2016.
• Ouyang D*, Chen J, Hom J, Chi J. “How Much Time Do Internal Medicine Residents Spend on the Computer?: An Electronic Audit of an Inpatient Service.” JAMA Internal Medicine., August 7, 2015. *Corresponding author
• Ouyang D*, I El-Sayed, SS Yom. National Trends in Surgery for Sinonasal Malignancy and the Effect of Hospital Volume on Short-Term Outcome. Laryngoscope. July 4, 2014.

Gender Disparities in Medicine

• Vranas KC*, Ouyang D*, Lin AL, Slatore CG, Sullivan DR, Prasad Kerlin M, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern S, Matthay MA, Herridge M, Mehta S, Rogers AJ. “Gender Differences in Authorship of Critical Care Literature.” Am J Respir Crit Care Med. January 22, 2020.
• Ouyang D*, Harrington RA, Rodriguez F. “The Association between Female Corresponding Authors and Female Co-Authors in Top Contemporary Cardiovascular Medicine Journals.” Circulation February 19, 2019.
• Ouyang D, Sing DC, Shah S, Duvernoy C, Harrington RA, Rodriguez F. “Gender Disparities in Authorship Order of Cardiology Scientific Publications – Trends over 40 Years.” Circulation Cardiovascular Quality and Outcome Dec 11, 2018.
• Sing DC, Jain D, Ouyang D. "Gender trends in authorship of spine-related academic literature - a 39-year perspective." Spine J. June 30, 2017

A complete list of publications is available at Google Scholar